Cloning and pharmacological characterization of a rat μ opioid receptor
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چکیده
منابع مشابه
Replacement of Serine363 and Serine375 Codons by Alanine in Rat μ-Opioid Receptor cDNA
The aim of this study was to use site directed mutagenesis technique to construct a vector in which serine363 and serine375 residues of the COOH-terminal portion of the μ-opioid receptor (MOR) were substituted by alanine. These constructs are essential in studying G-protein coupled receptor kinase-mediated MOR desensiti-zation. The nested PCR carried out for conversio...
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At least three types of opioid receptors have been identified in the nervous system. In this paper we report molecular cloning and expression of a rat K opioid receptor. PCR was performed on double-stranded cDNA derived from poly(A)+ RNA of the rat striatum with primers similar to those of Libert and co-workers [Libert, Parmentier, Lefort, Dinsart, Van Sande, Maenhaut, Simons, Dumont and Vassar...
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ژورنال
عنوان ژورنال: Neuron
سال: 1993
ISSN: 0896-6273
DOI: 10.1016/0896-6273(93)90120-g